Product Details:
Payment & Shipping Terms:
|
Product Name: | Aicar | Other Name: | Acadesine |
---|---|---|---|
Number: | 2627-69-2 | M.F.: | C9h14n4o5 |
M.W.: | 258.23 | Packaging: | Foil Bag Or Vial |
Appearance: | White Crystalline Powder | Assays: | 99% |
Shipping: | By Express (FedEx,UPS,DHL,EMS), By Air And By Sea | Payment: | Western Union, Money Gram, T/T And Paypal |
WhatsApp: | +8618873306038 | ||
High Light: | sarms raw powder,selective androgen receptor modulators |
AICAR Description:
AICAR (chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide) is a peptide, which is an intermediate within the generation of inosine monophosphate and directly related to metabolic regulation. The most important mechanism that AICAR is known for is its ability to block enzymes both in intracellular and extracellular levels, which, in turn, allows for an accelerated stimulation of glucose uptake and increase protein kinases in skeletal muscle tissue. These two functions allow for more energy conversion, which helps burn fat and also sustain output in activity. This is what scientists and athletes/bodybuilders are interested in, but there are some amazing side effects.
Interestingly, AICAR has been shown to protect against ischemic injury. This type of injury is directly related to the restriction of blood to tissues, which can cause insufficient amounts of oxygen and glucose needed to keep the tissue alive. This can lead to thrombosis, embolisms, and vasoconstriction. AICAR can be used as a stabilizing peptide for ischemic episodes, and it can allow for proper blood flow to the myocardium (heart). This function is very interesting, as AICAR could be fundamentally used to treat the heart muscle in the aftermath of a heart attack. This might reduce the possibility for ischemic injuries. Abnormal growths of heart tissues and heart valve function have also been altered in animal studies that used the peptide AICAR, which is a downside.
Specification:
Item | Specification | Result |
Appearance | White powder | Complies |
Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
Odor | Characteristic | Complies |
Assay | 99% | 99.8% |
Sieve analysis | 100% pass 80 mesh | Complies |
Loss on Drying Residue on Ignition |
≤1.0% ≤1.0% |
0.12% 0.09% |
Heavy Metal | <10ppm | Complies |
As | <0.1ppm | 0.05ppm |
Pb | <0.1ppm | 0.05ppm |
Cd | <0.1ppm | 0.05ppm |
Residual Solvents | <100ppm | Complies |
Residual Pesticide | Negative | Complies |
Microbiology | ||
Total Plate Count | <1000cfu/g | Complies |
Yeast & Mold | <100cfu/g | Complies |
E.Coli | Negative | Complies |
Salmonella | Negative | Complies |
Functions:
AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.
Dosage and Usage
Here is where AICAR becomes a pipe dream for anyone who is not a top level endurance athlete or bodybuilder. The dosages recommended to achieve the benefits from this peptide are insanely high. AICAR must be dosed at around 500mgs per kilogram (kg) of body weight. A gram of real pure AICAR can cost $100 USD or more, so single dosages for humans could be well in to the several hundreds of dollars! Some say that this can be circumvented by stacking it with Cardarine (GW), but you still need to spend a lot of money for perhaps little to no result if you are not dosing high enough dosages.
Yes, the peptide AICAR has amazing properties, some which even show the slowing of growth in cancer cells, but for the average athlete this has no basis in a day to day regiment. On the other hand, Cardarine (GW) has been shown to provide users with more than enough results as an Activated Receptor d agonists (PPARd) and it's cost-effective for everyone.
Side Effects
The most concerning side effects from AICAR are the direct effects it has on your heart. It can cause enlarged growth in cardiac tissue, and it can effect blood flow. In turn, this could affect the flow of blood to a person's brain. In addition, it has been noted that defects of heart valves may also be caused by the peptide AICAR. The heart is the most important muscle in the entire body, and the last thing anyone wants to do is treat it badly. Anecdotally, some logs indicated extreme loose bowls, dry mouth, and lack of hunger.
Possible enlarged growth of heart
Possible defects to the heart valve
Problems with blood flow
Problems with blood and nutrient transfer to the brain
Problems with bowls
----------------
ABOUT US
----------------
We're specialized in pharma.raw materials ( hormone steroid powders, Steroids injectable liquids,peptides,Sarms), our company integrates R&D, producing, operating and marketing into an organic whole. We have authority of export and import, and have experience of export for 15 years.
Major Market: United States, United Kingdom, Australia, Canada, Sweden, Russia, Poland, Brazil, Israel, Netherlands, Germany,Spain, Switzerland, Poland and so on.
MOQ:100ml
Package:Disguised & Discreet pkg
Payment:T/T,Western Union,Moneygram,bitcoin
Delivery: sent out the goods within 24hours after receiving payment.
Custom Pass rate:99%
Resend policy is available if the parcle is seized or any quality problems been found.
After-sale Service :
Discounts are available for our second-time customers. We can provide recipes and professional suggestions to promote yourselves. Tracking number and packing photos can be given quickly after your goods sent. We are always here waiting for you!
Our main products are wait for you:
Anabolic Steroid Powders
Semi-finished Steroid liquid
Peptides
Male enhancement powder
Pain Killer Powders
Nootropic Agent
SARMs
Fat Loss
Solvents for Steroids: BA, BB, GSO, Guaiacol, EO, PEG etc.
Tools & Devices: Filter,Crimper,Vials, caps, ect.
Contact Person: Lin.z