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selective androgen receptor modulators
Yk-11 induces myocytes to produce more follistatin, a potent myostatin inhibitor
Yk-11 is a little thinner than lgd-4033 and is an excellent equivalent to testosterone lean income.
For the treatment of muscle atrophy, and promote muscle growth is very large
Many users think YK11 is the key to unlocking the body’s full potential and achieving fast muscle gains with few side effects. YK11 appears to be a super-SARM based on the reviews, while in reality, this drug is NOT a typical SARM. This article breaks down the science and reviews to give you a clear idea of what to expect from this SARM-steroid hybrid, with risks and side effects.
YK11 is a new synthetic steroid based on 5-α-dihydrotestosterone (DHT), a hormone naturally found in the human body. DHT is a stronger form of testosterone that targets androgen receptors in the prostate, sex organs, hair, and liver.
YK11 is gaining interest from bodybuilders due to its ability to quickly build muscle with minimal side effects, much like various SARMs. The structure of YK11 is unique. The YK molecule shares more in common with steroids than SARMs, although it’s often mistakenly placed in the same bucket as all other non-steroidal SARM
One cellular study suggests that YK11 increases muscle mass. Researchers found that it increases the muscle-building protein follistatin (a myostatin inhibitor)
YK11 may also enhance bone health. In a study on bone cells, YK11 increased the levels of bone-building proteins
Some bodybuilders who have experimented with YK11 report great muscle gains and fat loss with minimal side effects. However, there are currently no animal or human studies of YK11 and its safety is unclear.
YK11, along with all steroids and SARMs, is banned in professional sports by the World Anti-Doping Agency
Bodybuilders and researchers sometimes refer to YK11 as a SARM (selective androgen receptor modulator). This may be misleading as other drugs that are traditionally called SARMs differ from YK11.
YK11 is a steroid made by directly altering the chemical structure of DHT. In contrast, all other SARMs have a nonsteroidal structure. YK11 and SARMs work differently in the body and may have different side effects
Cell studies do show that YK11 has a selective effect on androgen receptors. This means the SARM label does technically describe YK11
The chemical structure of YK11 is similar to DHT and it binds to androgen receptors in a similar way. DHT is a naturally occurring hormone in the body, crucial for hair growth, prostate health, proper development in puberty.
Some bodybuilding resources state that YK11 is one of the strongest SARMs on the market. However, research revealed that YK11 only partially activates androgen receptors and prevents full activation. Such limited activation increases the activity of catabolic androgenic genes
Importantly, YK11 is also a myostatin inhibitor. A recent cell study uncovered the basis of YK’s unique muscle-building mechanism: increasing follistatin levels. Follistatin is a naturally occurring protein in that suppresses myostatin, which otherwise prevents muscles from getting too large. In comparison, no other SARMs show myostatin inhibition
YK11 may also increase bone growth by affecting a DHT-like pathway, according to other cellular studies. YK11 activates protein kinase B (PKB), which sends signals to increase the activity of bone-building cells
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