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|Product Name:||Procaine||Other Name:||2-(Diethylamino)ethyl 4-aminobenzoate|
|M.W.:||236.31||Packaging:||Foil Bag Or Vial|
|Appearance:||White Crystalline Powder||Assays:||99%|
|Shipping:||By Express (FedEx,UPS,DHL,EMS), By Air And By Sea||Payment:||Estern Union, Money Gram, T/T And Paypal|
topical anesthetic drugs,
local anesthetic powder
Procaine may also be used for purposes other than those listed here.
Before using procaine, talk to your healthcare provider if you have
bleeding or blood clotting problems;
a neuromuscular disease such as myasthenia gravis; or
other serious medical conditions.
You may not be able to use procaine, or you may require a dosage adjustment or special monitoring during treatment.
It is not known whether procaine will be harmful to an unborn baby. Do not use procaine without first talking to your doctor if you are pregnant or could become pregnant during treatment.
It is not known whether procaine passes into breast milk. Do not use procaine without first talking to your doctor if you are breast-feeding a baby.
Your healthcare provider will administer procaine as an injection.
Procaine is administered as an injection in a hospital or clinic setting. Missing a dose should not apply.
Seek emergency medical attention if an overdose is suspected.
Since there will be decreased sensation of the area where procaine is injected, use caution to avoid injury to the area during and following treatment.
Before using procaine, talk to your doctor if you are taking any of the following medicines:
a monoamine oxidase inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate);
guanadrel (Hylorel) or guanethidine (Ismelin);
a medicine to treat high blood pressure; or
a medicine to improve muscle strength or tone for conditions such as myasthenia gravis.
You may not be able to use procaine, or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with procaine. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.
Used as a local anesthetic primarily in oral surgery
Procaine is an anesthetic agent indicated for production of local or regional anesthesia, particularly for oral surgery. Procaine (like cocaine) has the advantage of constricting blood vessels which reduces bleeding, unlike other local anesthetics like lidocaine. Procaine is an ester anesthetic. It is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis into para-aminobenzoic acid (PABA), which is then excreted by the kidneys into the urine.
Mechanism of action
Procaine acts mainly by inhibiting sodium influx through voltage gated sodium channels in the neuronal cell membrane of peripheral nerves. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is thus inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Procaine has also been shown to bind or antagonize the function of N-methyl-D-aspartate (NMDA) receptors as well as nicotinic acetylcholine receptors and the serotonin receptor-ion channel complex.
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|Lidocaine||Tetracaine hydrochloride||Bupivacaine hydrochloride|
|Linocaine hydrochloride||Pramoxine hydrochloride||Dibucaine hydrochloride|
|Procaine||Articaine hydrochloride||Ropivacaine hydrochloride|
|Procaine hydrochloride||Benzocaine hydrochloride||Levobupivacaine Hcl
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