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Pharma Solvents 1,4-Butanediol / BDO / BD Intermediates Liquid CAS 110-63-4

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Pharma Solvents 1,4-Butanediol / BDO / BD Intermediates Liquid CAS 110-63-4

China Pharma Solvents 1,4-Butanediol / BDO / BD Intermediates Liquid CAS 110-63-4 supplier

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Place of Origin: Hubei, China
Brand Name: saichuang
Certification: ISO9001, USP, BP, GMP
Model Number: Solvent

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Minimum Order Quantity: 100ml
Price: Negotiate
Packaging Details: discreet package or as required
Delivery Time: 5~8 working days
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: 5000KG/week
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Detailed Product Description
Name: 1,4-Butanediol Appearance: Liquid
Assay: 99% Min. MOQ: 100ml
Grade: Pharma Grade Package: Safety And Discreet Pkg
Payment: T/T,Money Gram,Western Union,Bitcoin Delivery: Within 24hours After Payment
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Pharma Solvents 1,4-Butanediol / BDO / BD Intermediates Liquid CAS 110-63-4
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1,4-Butanediol Basic information
Product Name: 1,4-Butanediol
Synonyms: sucolb;Tetramethylene 1,4-diol;tetramethylene1,4-diol;1,4-dilhydroxybutane;1,4-Butylene glycol~Tetramethylene glycol;1 4-BUTANEDIOL REAGENTPLUSTM >=99%;1 4-BUTANEDIOL REAGENTPLUS 99%;1,4-Butanediol 4 M Solution
CAS: 110-63-4
MF: C4H10O2
MW: 90.12
EINECS: 203-786-5
Product Categories: Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Polyols;Solvents;Solvent;1,4 BDO;solvents and intermediates
Mol File: 110-63-4.mol
1,4-Butanediol, colloquially known as BD, is the organic compound with the formula HOCH2CH2CH2CH2OH. It is a colorless viscous liquid. It is one of four stable isomers of butanediol.


In its industrial synthesis, acetylene reacts with two equivalents of formaldehyde to form 1,4-butynediol. This type of acetylene-based process is illustrative of what is known as "Reppe chemistry", after German chemist Walter Reppe. Hydrogenation of 1,4-butynediol gives 1,4-butanediol. This route is used by BASF and Ashland/ISP. It is also manufactured on an industrial scale from maleic anhydride in the Davy process, which is first converted to the methyl maleate ester, then hydrogenated. Other routes are from butadiene, allyl acetate and succinic acid.

A biological route to BDO has been commercialized that uses a genetically modified organism.The biosynthesis proceeds via 4-hydroxybutyrate.

Industrial use

1,4-Butanediol is used industrially as a solvent and in the manufacture of some types of plastics, elastic fibers and polyurethanes. In organic chemistry, 1,4-butanediol is used for the synthesis of γ-butyrolactone (GBL). In the presence of phosphoric acid and high temperature, it dehydrates to the important solvent tetrahydrofuran. At about 200 °C in the presence of soluble ruthenium catalysts, the diol undergoes dehydrogenation to form butyrolactone.

World production of 1,4-butanediol was claimed to be about one million metric tons per year and market price is about 2,000 USD (1,600 EUR) per ton (2005). In 2013, worldwide production was claimed to be billions of lbs (consistent with approximately one million metric tons).

Almost half of it is dehydrated to tetrahydrofuran to make fibers such as Spandex. The largest producer is BASF.

Toxicity and use as a recreational drug

FDA warning against products containing GHB and its prodrugs, such as 1,4-butanediol.

1,4-Butanediol is also used as a recreational drug known by some users as "One Comma Four", "Liquid Fantasy", "One Four Bee" or "One Four B-D-O". It exerts effects similar to γ-hydroxybutyrate (GHB), which is a metabolic product of 1,4-butanediol. When mixed with other drugs, misuse of 1,4-butanediol has resulted in addiction and death.


1,4-Butanediol Chemical Properties
Melting point 20 °C
Boiling point 230 °C(lit.)
density 1.017 g/mL at 25 °C(lit.)
vapor density 3.1 (vs air)
vapor pressure <0.1 hPa (20 °C)
refractive index n20/D 1.445(lit.)
Fp 135 °C
storage temp. 2-8°C
PH 7-8 (500g/l, H2O, 20℃)
explosive limit 1.95-18.3%(V)
Water Solubility Miscible
Sensitive Hygroscopic
BRN 1633445
Stability: Stable. Combustible. Incompatible with strong oxidizing agents, mineral acids, acid chlorides, acid anhydrides.
CAS DataBase Reference 110-63-4(CAS DataBase Reference)
NIST Chemistry Reference 1,4-Butanediol(110-63-4)
EPA Substance Registry System 1,4-Butanediol(110-63-4)
Safety Information
Hazard Codes Xn
Risk Statements 22-67
Safety Statements 36-23-24/25
WGK Germany 1
RTECS EK0525000
Autoignition Temperature 698 °F
HS Code 29053980
Pharma Solvents 1,4-Butanediol / BDO / BD Intermediates Liquid CAS 110-63-4

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Pharma Solvents 1,4-Butanediol / BDO / BD Intermediates Liquid CAS 110-63-4
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