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|Product Name:||S23||Other Name:||S+23|
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selective androgen receptor modulators
S23 or (2S)-N-(4-cyano-3-trifluoromethylphenyl)-3-(3-fluoro-4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide is a new SARM from GTX, Inc. which is developed as a possible male hormonal contraceptive. It links to the androgen receptor (AR) more intensely (with a Ki of 1.7nM) as compared to older medicines such as Andarine.
In animal research, S23 displayed a good ratio of anabolic to androgenic effects as well as dose-dependent restraint of spermatogenesis (the course of sperm cell development) with unprompted recuperation after end of treatment.
S-23 is an investigational SARM, as a potential male hormonal contraceptive. It binds to the receptor more strongly than older drugs such as andarine with a Ki of 1.7 nM, and in animal studies it showed both a good ratio of anabolic to effects, and dose-dependent suppression of spermatogenesis with spontaneous recovery after cessation of treatment.
How safe is S23 ?
Many people want to know S-23's safety before any action is made. Most of these SARMs have not yet been tested on humans, but only on rats or mice. This is also true for S23.
SARM 23 can be found in some webstores that sell research chemicals online. Not much is known about the working or side effects of SARMs in humans, so caution is advised. And a 2009 animal study, in which researchers at GTx tried S23 out on rats, suggests that S23 is a little more risky than other SARMS.
S-23 not only boosted muscle mass, but also reduced fat mass, as studied. SARMs have a bit of a 'soft' image in the doping world. They don't stimulate muscle growth in the way that anabolic steroids do, but many users say that they are safer.
There are no studies yet that confirm this suspicion. But that S23 is not one of the safer SARMs - we'd be willing to wager a bottle of BCAAs on that. S23 halts the production of sperm in the testes. In fact it does this so well that the researchers suspect S23 might be a good candidate for a male contraceptive. If this is the case it would probably have to be part of a cocktail that also contains an estradiol analogue, the researchers discovered. The lab animals lost their libido when they were given S23 on its own, and only recovered this when they were given estradiol benzoate together with the S23.
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