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|Product Name:||GW501516||Other Name:||Cardarine|
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GW-501516 (Cardarine, GW1516 or GSK-516) acts as a PPARδ modulator compound. GW 501516 activates AMP-activated protein kinase and stimulates glucose uptake in skeletal muscle tissue.
GW 501516 (or Cardarine) is a research chemical developed to prevent and cure tumor formation in the colon, prostate, and breasts. Studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to stop metabolic disorders such as obesity and diabetes through specific gene expressions.
As research continued to grow, bodybuilders quickly caught on to GW 501516, calling it the ultimate endurance enhancing supplement. GW’s ability to burn off excess fatty tissue, enhance recovery, and dramatically increase endurance has made this product a staple in every athlete’s cycle and PCT. With no harmful side effects found in the past 20 years, no wonder why GW 501516 has become a legend in the world of sports and athleticism.
Product Name: 2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid
Synonyms: 2-(4-((2-(4-(TRIFLUOROMETHYL)PHENYL)-5-METHYLTHIAZOL-4-YL)METHYLTHIO)-2-METHYLPHENOXY)ACETIC ACID;2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic Acid;Methyl-methyl-trifluoromethylphenyl -thiazolyl-methylsulfanyl-phenoxy-acetic Acid;2-(4-((2-(4-(trifluoromethyl)phenyl)-4-methylthiazol-5-yl)methylthio)-2-methylphenoxy)acetic acid;GW 1516;2-(2-methyl-4-((5-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-4-yl)methylthio)phenoxy)acetic acid;GW501516, Free Acid;GSK-516
Appreance:Chemical Properties White Solid
Usage :For obesity, diabetes, dyslipidemia and cardiovascular disease
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
You probably have a gym buddy who raves about how Cardarine (GW 501516) helped him with endurance. Most of us hate long distance cardio, but we feel great after. This drug helps a lot with that and has been adopted as the standard in endurance sports.
It is not known who leaked Cardarine (GW-501516) to athletes, or when they started using it. It could have been as early as the mid 90’s. All we know for certain is that word spreads fast and by the 2008 Chinese Olympics, a large percentage of athletes were using it to dope, with great success. The next year it was banned by just about all doping commissions, but many athletes still take the risk and use it anyway because it is so effective.
Cardarine (GW 501516) is NOT a SARM (selective androgen receptor modulator). Rather it is a Peroxisome proliferator-activated receptor beta (PPAR) agonist which binds to those receptors. This means the activity in the gene is changed, causing a shift in how energy is put out. This translates into an ability to push harder and longer when it comes to endurance, without becoming winded. This can help you not just with cardio/running, but also in the weight room since you can push out another repetition and workout for longer without becoming tired.
Keep in mind this mode of action is not like taking a stimulant which sharply increases your heart rate and actually causes you to get winded faster. Cardarine (GW501516) does the opposite, you are able to rev up the engine more, without spiking your heart rate.
Another big thing I want to touch on also is fat loss. Whether you are lean already, average size, or flat out obese, you can use Cardarine (GW 501516) safely to help burn away fat. Again it works very different from stimulant based fat burners. Instead, the way it works is by altering how the body reacts to the food you eat because it spikes glucose intake. This means even users who eat poorly can still lose body fat on it, however, the studies do show the better you eat and the more you exercise the sharper your results. In the end, it makes it much easier to lose fat no matter your diet.
Cardarine (GW501516) is not a hormone, it doesn’t cause heart strain, and it doesn’t aromatize into estrogen. Human studies have shown no issues when used even up to 6 months straight.
Cardarine (GW-501516) can be used by itself. I recommend using 10-20mgs a day with some users choosing to dose it about 2-3 hours prior to their exercise. Expect a major boost to your endurance with users reporting a 30-45 second improvement on their 5K runs within 2 weeks of starting the compound. Fat loss benefits have been reported by users after 4-5 weeks using the drug.
Trenbolone is notorious for destroying endurance due to its inflammatory nature. In fact, all anabolic steroids increase inflammation in the body and can cause a loss of endurance. Due to this factor experienced anabolic users have found that stacking in 20mgs a day of Cardarine (GW 501516) will result in a stark difference in how winded they become during a workout.
I believe that using Cardarine (GW501516) as your base in a SARM cycle is a wise choice. The reason is it will boost endurance and increase fat loss, both things everyone wants, without increasing side effects. I recommend 10-20mgs a day.
You can also use this drug during your post cycle therapy because it is completely nonhormonal. It will help prevent any sort of fat rebound while your body is most vulnerable. It also will keep you motivated to workout. I recommend 10-20mgs a day.
Although it has been found to be safe in human trials for up to 6 months, remember Cardarine (GW-501516) is still a drug and should be respected. I recommend using for up to 12 weeks only, and cycling off 4-6 weeks. After you come off you can come back on for 12 more weeks and so on.
The half-life is 24 hours so once a day dosing is adequate. As far as detection times it is unclear how long it will show up in a doping test, the assumption is up to 1 month. However, keep in mind cheating in sports is wrong and gives you an unfair advantage over your opponents. I am against doping and you will get caught eventually.
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